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The effect of intravesically applied antibiotic solution in the prophylaxis of infectious complications of renal transplantation

✍ Scribed by K. Salmela; B. Eklund; L. Kyllönen; H. Isoniemi; H. Korsbäck; K. Höckerstedt; J. Ahonen


Publisher
Springer
Year
1990
Tongue
English
Weight
317 KB
Volume
3
Category
Article
ISSN
0934-0874

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✦ Synopsis


The effect of intravesically applied antibiotic solution in the prevention of infectious complications of renal transplantation was evaluated in a prospective, randomized study. The bladder was filled preoperatively with saline solution containing cephalotin in the test group, and with saline solution only in the controls. Both groups of patients received IV doses of cephamandole during, and once after, surgery. Two hundred consecutive patients were randomly allocated to the study groups. The overall incidence of urinary tract infection was 10.4% during the first 4 postoperative weeks; that of wound infections was 1.6% and of septicemia 3.3%. The addition of cephalotin to the bladder irrigation fluid did not have any effect on the overall incidence of infectious complications.


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