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The effect of interleukin-1 blockade on fatigue in rheumatoid arthritis—a pilot study

✍ Scribed by Roald Omdal; Ragnar Gunnarsson

Publisher
Springer
Year
2004
Tongue
English
Weight
193 KB
Volume
25
Category
Article
ISSN
0172-8172

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## Abstract ## Objective Interleukin‐21 (IL‐21) is a T cell–derived cytokine that modulates T cell, B cell, and natural killer cell responses. In this study, the effects of blocking IL‐21 were examined in 2 rodent models of rheumatoid arthritis (RA) to determine whether IL‐21 contributes to their