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The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle

✍ Scribed by Xuxia Wu; Jelai Wang; Xiangqin Cui; Lidia Maianu; Brian Rhees; James Rosinski; W. Venus So; Steven M. Willi; Michael V. Osier; Helliner S. Hill; Grier P. Page; David B. Allison; Mitchell Martin; W. Timothy Garvey

Book ID
107571068
Publisher
Springer
Year
2007
Tongue
English
Weight
374 KB
Volume
31
Category
Article
ISSN
0969-711X

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## Abstract In humans and animal models, increased intramuscular lipid (IML) stores have been implicated in insulin resistance. Malonyl‐CoA plays a critical role in cellular lipid metabolism both by serving as a precursor in the synthesis of lipids and by inhibiting lipid oxidation. In muscle, Malo