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The Effect of Insulin-Like Growth Factor I on Healing of Colonic Anastomoses in Cortisone-Treated Rats

โœ Scribed by I. Mantzoros; I. Kanellos; S. Angelopoulos; G. Koliakos; M. G. Pramateftakis; D. Kanellos; E. Zacharakis; T. Zaraboukas; D. Betsis


Publisher
Springer
Year
2006
Tongue
English
Weight
230 KB
Volume
49
Category
Article
ISSN
0012-3706

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## Abstract ## BACKGROUND High concentrations of insulinโ€like growth factor (IGF)โ€I and IGFโ€II have been demonstrated in human colonic adenocarcinomas and exert mitogenic effects through paracrine/autocrine interactions with the IGFโ€I receptor (IGFโ€IR). However, definitive studies of IGFโ€IR expres