𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The effect of injections of dopaminergic agonists into the caudate nucleus on the electrocorticogram of the rat

✍ Scribed by Dr. P. E. Keane; Dr. H. Neal

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
299 KB
Volume
6
Category
Article
ISSN
0360-4012

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Electrocortical activity was recorded in encΓ©hale isolΓ© rats during injection of various dopaminergic compounds into the caudate nucleus. Slow waves and spindles were observed following injection of compounds with different mechanisms of action in stimulating the dopamine receptor. Some arylalkylamine analogues also induced similar electrocortical changes, whereas others were inactive. The possible dopamine agonist activities of these compounds are discussed. The results support an involvement of dopamine in the production of electrocortical slow waves and spindles.

πŸ“œ SIMILAR VOLUMES

Effect of acute and chronic fluoxetine o
Effect of acute and chronic fluoxetine on extracellular dopamine levels in the caudate-putamen and nucleus accumbens of rat
✍ Robert N. Clark; Charles R. Ashby Jr.; Stephen L. Dewey; P. Veeraraghavan Ramach πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 710 KB

Recent studies indicate that an increase in serotonergic (5-HT) activity in the nucleus accumbens (NAc) produces an increase in dopamine (DA) release, providing a possible mechanism for the involvement of DA in the therapeutic action of selective serotonin reuptake inhibitor (SSRI) antidepressants.

Effect of sertindole on raised mesolimbi
Effect of sertindole on raised mesolimbic dopaminergic activity in the rat
✍ Annette M. Domeney; JΓΆrn Arnt; Brenda Costall; Robert J. Naylor; Connie SΓ‘nchez; πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 843 KB

The effect of sertindole in models of mesolimbic dopamine excess in the rat was evaluated. Sertindole (0.0057-0.011 pmol/kg = 2.5-5 pg/kg, SC) and haloperidol (0.134.27 pmol/kg = 50-100 pg/kg, ip) inhibited the hyperactivity caused by the acute intra-accumbens injection of amphetamine (20 pg). The a

Distribution and synaptic organization o
Distribution and synaptic organization of dopaminergic axons in the lateral geniculate nucleus of the rat
✍ Georgios C. Papadopoulos; John G. Parnavelas πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 686 KB

## Abstract In the present study, immunocytochemistry with an antiserum against dopamine (DA) revealed hitherto unknown terminal fields of DA axons in the lateral geniculate nucleus (LGN) of the rat. The innervation of all subdivisions of the LGN is achieved by a common set of afferent fibers that

Effects of risperidone and haloperidol o
Effects of risperidone and haloperidol on tachykinin and opioid precursor peptide mRNA levels in the caudate-putamen and nucleus accumbens of the rat
✍ M. Janneke Mijnster; Alain Schotte; Gerrit J. Docter; Pieter Voorn πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 323 KB πŸ‘ 2 views

We investigated whether the two output pathways of the striatum are differently affected by the novel atypical drug risperidone and the conventional typical antipsychotic drug haloperidol. To this end, changes in mRNA levels of preproenkephalin-A, preproenkephalin-B, and preprotachykinin were determ