The effect of indocyanine green pretreatment on the parameters of transscleral diode laser thermotherapy-induced threshold coagulation of the ciliary body
✍ Scribed by Po-Cheng Kuo; Gholam A. Peyman; Gamze Men; Yanno Bezerra; Franco Torres
- Book ID
- 102464979
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 247 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0196-8092
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✦ Synopsis
Abstract
Background and Objective
To study the effect of indocyanine green (ICG) pretreatment on threshold parameters of transscleral diode laser thermotherapy‐induced threshold coagulation of the ciliary body. The procedure was termed ‘cyclothermotherapy’ based on the long duration (15–60 seconds) of diode laser application.
Study Design/Materials and Methods
The right eyes of nine young adult New Zealand white rabbits underwent transscleral cyclothermotherapy (TCT, Group 1), TCT following ICG pretreatment (Group 2), and external manipulation of the ciliary body alone (Group 3). Rabbits were sacrificed after 24 hours; specimens were evaluated with gross examination and light microscopy.
Results
Thresholds were 30 J/cm^2^ (TCT) and 4.5 J/cm^2^ (TCT with ICG). Widespread structural damage was seen in the ciliary processes and the ciliary body in Groups 1 and 2. In Group 3, external manipulation of the ciliary body caused hemorrhage and structural damage confined to the ciliary processes.
Conclusion
ICG pretreatment reduced the energy necessary to cause a threshold lesion with TCT in nonpigmented rabbits. Lasers Surg. Med. 35:157–162, 2004. © 2004 Wiley‐Liss, Inc.