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The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer’s disease

✍ Scribed by M.L. Selley; D.R. Close; S.E. Stern

Book ID: 117412270
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 56 KB
Volume: 23
Category: Article
ISSN: 0197-4580
DOI: 10.1016/s0197-4580(01)00327-x

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## Abstract To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8‐hydroxyguanosine (8‐OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and control subjects. T