## Abstract Cholera toxin inhibits human natural cell‐mediated cytotoxicity in a dose‐ and time‐dependent manner. Pretreatment of lymphocytes with 10 ng/ml of cholera toxin for 2 h almost completely inhibited cytolysis. Interferon augmented human natural cell‐mediated cytolysis, but when lymphocyte
✦ LIBER ✦
The effect of immunopharmacological agents on mouse natural cell-mediated cytotoxicity and on its augmentation by poly I:C
✍ Scribed by Julie Y. Djeu; Jeffrey A. Heinbaug; Wilfred D. Vieira; Howard T. Holden; Ronald B. Herberman
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 806 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0162-3109
No coin nor oath required. For personal study only.
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## Abstract Treatment of rats with high doses of hydrocortisone, X‐irradiation, or cyclophosphamide had a suppressive effect on natural cytotoxicity __in vivo__. However, when rats were given poly I:C ^3^ after any of these agents, the levels of NK activity were similar to those in normal rats whic