Effect of a poly(ADP-ribose) polymerase
β
LuΓsa CristΓ³vΓ£o; JosΓ© Rueff
π
Article
π
1996
π
John Wiley and Sons
π
English
β 695 KB
The activity of poly(ADP-ribose) polymerase (PARP) is activated upon recognition of DNA strand breaks by its DNA-binding domain and the stimulation of this nuclear enzyme seems to be an early response of cells exposed to a variety of different DNA-damaging agents. In the present work we evaluate the