The effect of hyaluronic acid on cartilage in the immobilized rabbit knee
✍ Scribed by Olsenl, Elith Bjarne ;Trier, Klaus ;Jørgensen, Bjarne ;Brok, Karl-Erik ;Ammitzbøll, Thorkil
- Book ID
- 121836635
- Publisher
- Informa plc
- Year
- 1991
- Tongue
- English
- Weight
- 262 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0001-6470
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## Abstract Thirteen adult female rabbits underwent unilateral osteotomy of the proximal tibia. In nine animals, 30° of valgus angulation was created; in four animals, osteotomy without angulation was performed. After a 12‐week survival period, the knee joints were processed for histology by staini
The protein-keratan sulfate core of bovine nasal cartilage proteoglycan was purified by affinity chromatography on a column of immobilized hyaluronic acid. The hyaluronic acid was immobilized by reaction with a hydrazido-alkyl derivative of Sepharose in the presence of borohydride. Proteoglycan was