The effect of hip replacement on prescribing of NSAIDs, ulcer healing drugs and hospitalization—a matched cohort study
✍ Scribed by Peter G. Davey; Alex D. McMahon; Fabio Barbone; William G. Gillespie; K. A. Rizvi; Thomas M. MacDonald
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 112 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1053-8569
No coin nor oath required. For personal study only.
✦ Synopsis
Purpose Ð To assess the impact of total hip replacement on prescribing of non-steroidal anti-in¯ammatory drugs (NSAIDs), ulcer healing drugs (UHDs) and hospitalization.
Methods Ð Observational matched cohort study.
Results Ð There were 282 subjects in the hip replacement cohort and 1691 in the comparator cohort. Dispensing of NSAIDs fell from 89% to 57% after hip replacement but increased from 36% to 39% in comparators. Dispensing of UHDs fell from 33% to 30% after hip replacement but increased from 16% to 23% in the comparators. Hospitalization for upper gastrointestinal events fell from 2.5% to 1.8% after hip replacement but increased from 1.4% to 1.7% in comparators. Hospitalization for other causes increased from 32% to 42% after hip replacement compared with 25% to 28% in comparators.
Conclusions Ð Hip replacement is associated with reduced prescribing of NSAIDs and UHDs. However, any eect on GI admissions will be small compared with increased hospitalization for other causes.