The effect of heparin on fibronectin and thrombospondin synthesis by human smooth muscle cells
โ Scribed by Bernadette Lyons-Giordano; Helen Conaway; Nicholas A. Kefalides
- Book ID
- 117057623
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 896 KB
- Volume
- 148
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
Heparin suppresses the proliferation of vascular smooth muscle cells both in vivo and in vitro. The mechanism of action of the antiproliferative activity of heparin is not known. We have detected differences in the synthesis of specific proteins when vascular smooth muscle cells are exposed to hepar
## Abstract Previous work from our laboratory has shown that heparin inhibits the proliferation of vascular smooth muscle cells in vivo and in vitro. The mechanism of action of this glycosaminoglycan is unknown. In this communication, we have examined the antiproliferative effect of heparin on smoo