## Abstract Much research has focused on the differentiation of human mesenchymal stem cells (hMSCs) in monolayer culture; however, little is known about their differentiation potential in threeβdimensional culture conditions. In this research, hMSCs were encapsulated in a photocrosslinkable, injec
The effect of heparin-functionalized PEG hydrogels on three-dimensional human mesenchymal stem cell osteogenic differentiation
β Scribed by Danielle S.W. Benoit; Andrew R. Durney; Kristi S. Anseth
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 386 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0142-9612
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Stem cells are regulated not only by soluble stimuli but also the less well studied physical microenvironment. [1] The physical niche is a combination of structural, cellular, and biochemical components that vary among tissues and contribute to control proliferation and differentiation. [2] Cells fu
## Abstract Layerβbyβlayer assembly of biogenic polyelectrolytes (PEL) was carried out on the surface of poly (Lβlactide) to generate polyelectrolyte multilayers (PEM) that foster osteogenic differentiation of human mesenchymal stem cell (hMSC). Gelatin (GEL), hyaluronic acid (HA) and heparin (HEP)
## Abstract __Ex vivo__ engineering of autologous bone tissue as an alternative to bone grafting is a major clinical need. In the present study, we evaluated the effect of 3βD dynamic spinner flask culture on the proliferation, distribution, and differentiation of human mesenchymal stem cells (MSCs
## Abstract Human mesenchymal stem cells (hMSCs) are characterized by their abilities to differentiate into different lineages, including osteoblasts. Besides soluble factors, mechanical strain and extracellular matrix (ECM) proteins play important roles in osteogenic differentiation of hMSCs. Howe
Embryonic stem cells represent a potentially unlimited cell source for tissue engineering applications. However, in order to be used for such applications, embryonic stem cells' differentiation must be controlled to only the desired lineages. In this study, we examine the effects of nanofibrous arch