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The effect of growth factors on both collagen synthesis and tensile strength of engineered human ligaments

โœ Scribed by Paul Hagerty; Ann Lee; Sarah Calve; Cassandra A. Lee; Martin Vidal; Keith Baar

Book ID
113492128
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
752 KB
Volume
33
Category
Article
ISSN
0142-9612

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Effect of mechanical factors on the func
Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels
โœ Gavrielle M. Price; Keith H.K. Wong; James G. Truslow; Alexander D. Leung; Chitr ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 886 KB

This work examines how mechanical signals affect the barrier function and stability of engineered human microvessels in microfluidic type I collagen gels. Constructs that were exposed to chronic low flow displayed high permeabilities to bovine serum albumin and 10 kDa dextran, numerous focal leaks,