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The effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on primitive hematopoietic stem cell (PHSC) function and numbers, after chemotherapy

✍ Scribed by Renee Vanessa Gardner; Rodolfo Begue; Evangeline McKinnon

Book ID
114216681
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
72 KB
Volume
29
Category
Article
ISSN
0301-472X

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Granulocyte-macrophage colony-stimulating factor (GM-CSF) (250 microg/m2) was administered subcutaneously to 7 normal volunteers for up to 14 days to study its effects on neutrophil kinetics and function. With treatment, blood neutrophil counts rose gradually to peak at 3 1/2 times baseline by day 1