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The Effect of Gelatin Cross-Linking on the Bioequivalence of Hard and Soft Gelatin Acetaminophen Capsules

✍ Scribed by Marvin C. Meyer; Arthur B. Straughn; Ramakant M. Mhatre; Ajaz Hussain; Vinod P. Shah; Carey B. Bottom; Ewart T. Cole; Larry L. Lesko; Henry Mallinowski; Roger L. Williams

Book ID
110251825
Publisher
Springer US
Year
2000
Tongue
English
Weight
139 KB
Volume
17
Category
Article
ISSN
0724-8741

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The present study investigated the effect of lipophilic components on the compatibility of propylene glycol (PG)-containing lipid-based drug delivery system (LBDDS) formulations with hard gelatin capsules. The presence of a lipophilic active pharmaceutical ingredient (API) (log P approximately 6.1)