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The effect of fluoride on the scavenging of organophosphates by human butyrylcholinesterase in buffer solutions and human plasma

โœ Scribed by Yacov Ashani; Omri Segev; Ayala Balan


Book ID
113923184
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
285 KB
Volume
194
Category
Article
ISSN
0041-008X

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In humans, the plasma enzyme butyrylcholinesterase, BChE (EC 3.1.1.8), mediates the in vivo plasma hydrolysis of cocaine to the pharmacologically inactive metabolite ecgonine methyl ester, EME. This enzyme has been purified from human plasma to investigate the potential as a treatment for cocaine in