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The effect of five proteins on stem cells used for osteoblast differentiation and proliferation: a current review of the literature

✍ Scribed by Chatakun, P.; NÃºÃ±ez-ToldrÃ , R.; DÃaz LÃ³pez, E. J.; Gil-Recio, C.; MartÃnez-SarrÃ , E.; HernÃ¡ndez-Alfaro, F.; FerrÃ©s-PadrÃ³, E.; Giner-Tarrida, L.; Atari, M.

Book ID: 120168439
Publisher: Springer
Year: 2013
Tongue: English
Weight: 442 KB
Volume: 71
Category: Article
ISSN: 1420-682X
DOI: 10.1007/s00018-013-1326-0

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## Abstract PC12 rat phaeochromocytoma cells show neuronal differentiation upon NGF treatment. NGF induces prolonged activation of the Ras/Raf/MEK/ERK pathway in which the 42/44 kDa mitogen‐activated protein kinases (MAPKs), ERK 1 and 2 are thought to be the key mediators of the differentiation sig