The effect of feeding ventriculin to pregnant rats, with special reference to the size of the red blood cells of the young

✍ Scribed by Briese, Estelle ;Higgins, George M.

• Publisher: John Wiley and Sons
• Year: 1939
• Tongue: English
• Weight: 444 KB
• Volume: 73
• Category: Article
• ISSN: 0003-276X
• DOI: 10.1002/ar.1090730109

✦ Synopsis

ONE F'IGURE

12ed blood corpuscles in newborn animals a r e always larger than those in the adult. The number of i-ed cells per cubic millimeter of blood is less than in the adult; so that a condition normally exists in fetuses, as ~i d l as in tlie young, which may be called a physiologic mncrocytosis. As gi.owtl1 occurs, tlie red cells gradually increase in number per cubic centimeter and decrease in size until the adult condition is reached. In white rats the red cells of the iiewhorn in dry smears rncasure approximately 10 p in diametw and have a nieuii corpuscular volume of about 150 pt3. X T h n the animals are 70 to 80 days of age thc average diameter of the red cells is slightly more than 6 p and tlw corpuscular volume is about 50 p3. Wintrobe and Shumackcr ('35) expTessed tile opinion that these changes which occur in the blood during iiormal development r.esrmb1~ the changes which occur in patients suffering from pernicioiis anemia who are subjected to some stimulus f o r blood formation.