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The effect of exposure duration on the blood level of glucose pyruvate and lactate in acute carbon monoxide intoxication in man

✍ Scribed by J. A. Sokal

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
252 KB
Volume
5
Category
Article
ISSN
0260-437X

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✦ Synopsis

Blood glucose, pyruvate and lactate were examined during hospitalization of 13 cases of acute carbon monoxide poisoning developing from short (< 1.5 h) or long (10-14 h) exposure. CO intoxication resulted in increased blood levels of all carbohydrate metabolites studied. Increased levels of pyruvate and lactate were much more pronounced and lasted for a longer time following long, compared with short, CO exposure despite similar blood COHb level (about 40% at the beginning of hospitalization).

The results showed difference in biochemical effect of short and long single exposure to CO that could not be detected by the measurement of COHb.

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