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The effect of exogenous gangliosides on matrix metalloproteinase secretion by human glioma cells in vitro

โœ Scribed by S.L. Maidment; A. Merzak; S. Koochekpour; H.K. Rooprai; G.J. Rucklidge; G.J. Pilkington

Book ID
116166715
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
561 KB
Volume
32
Category
Article
ISSN
0959-8049

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Glioma invasion into the surrounding brain tissue is still a major obstacle for any therapeutical approach. As in other solid tumors, matrix-metalloproteases (MMPs) have been suggested as being involved. The aim of this study was to evaluate whether the use of MMP inhibitors to target the protease-m