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The effect of EGF and the comitogen, norepinephrine, on the proliferative responses of fresh and cryopreserved rat and mouse hepatocytes

✍ Scribed by Julie A. Price; John Caldwell; Nicola J. Hewitt


Book ID
116392417
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
178 KB
Volume
53
Category
Article
ISSN
0011-2240

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Activin A, an autocrine factor produced by hepatocytes, inhibits mitogen-stimulated DNA synthesis and induces apoptotic death of cultured rat hepatocytes. Several lines of evidence indicate that norepinephrine (NE), as a comitogenic growth factor, alters the balance between growth stimulation and in