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The effect of Ecstasy on memory is moderated by a functional polymorphism in the cathechol-O-methyltransferase (COMT) gene

✍ Scribed by Thelma Schilt; Maarten W.J. Koeter; Maartje M.L. de Win; Janneke R. Zinkstok; Thérèse A. van Amelsvoort; Ben Schmand; Wim van den Brink


Book ID
118436967
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
317 KB
Volume
19
Category
Article
ISSN
0924-977X

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Putative role of the COMT gene polymorph
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## Abstract Working memory has been described as a neurocognitive probe of prefrontal brain functioning. Genetic variability related with catechol‐__O__‐methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention as a possible modulator of working memory tasks in both s