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The effect of doxorubicin treatment on the antioxidant activities of friend erythroleukemia cells sensitive or resistant to the drug

✍ Scribed by Crescimanno, M.; D'Alessandro, N.; Armata, M.G.; Tapiero, H.

Book ID
123146630
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
71 KB
Volume
22
Category
Article
ISSN
1043-6618

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## Abstract Multidrug resistant (MDR) tumor cells exhibit an altered pH gradient across different cell compartments, which favors a reduced intracellular accumulation of antineoplastic drugs and a decreased therapeutic effect. In our study, we have observed that the activity and expression of Na^+^