The effect of dopamine receptor blockade in the rodent nucleus accumbens on local field potential oscillations and motor activity in response to ketamine
β Scribed by Pawel Matulewicz; Stefan Kasicki; Mark Jeremy Hunt
- Book ID
- 113505287
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 878 KB
- Volume
- 1366
- Category
- Article
- ISSN
- 0006-8993
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Stress stimulates dopamine (DA) release in nucleus accumbens (NAcc) but will do so more strongly in medial prefrontal cortex (PFC). Evidence indicates, however, that the cortical DA response to stress acts to dampen the concurrent increase in NAcc DA release. In the present study, we used voltammetr
The present experiments assessed the acute and delayed effects of D-1 dopamine (DA) receptor blockade in the medial prefrontal cortex (mPFC) on pre-and postsynaptic indices of DA neurotransmission in the nucleus accumbens (N.Acc). Different groups of rats received intra-mPFC injections of saline (co