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The effect of DNA topoisomerase inhibitor-loaded films on postsurgical adhesion formation in the rat

✍ Scribed by J.D. Cashman; C.M. Springate; H.M. Burt; J.K. Jackson


Book ID
118444282
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
22 KB
Volume
82
Category
Article
ISSN
1556-5653

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The objective of the research was to determine the effect of the type, dose, and volume of anti-fibrinolytic agents (tranexamic acid, aprotinin) added to fibrin formulations, on adhesion development. Adhesions were induced in 228 male rats by creating apposing parietal and visceral peritoneal defect