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The effect of DNA hypomethylating agents on the reactivation of herpes simplex virus from latently infected mouse ganglia in vitro

✍ Scribed by A. J. Whitby; W. A. Blyth; T. J. Hill


Publisher
Springer Vienna
Year
1987
Tongue
English
Weight
605 KB
Volume
97
Category
Article
ISSN
1432-8798

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Reactivation of herpes simplex virus (HSV) was assumed to be dependent on prostaglandin synthesis [Kurane et al. (1984) J Gen Virol 65: 1665-1674]. Since free radicals are generated in the course of prostaglandin synthesis and inhibitors of prostaglandin synthesis are free radical scavengers, the qu