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The effect of digestion with phospholipase C on intrinsic protein phosphorylation in synaptic plasma membrane fragments

✍ Scribed by Ayṡe Döṡemeci; Richard Rodnight

Book ID
115913413
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
456 KB
Volume
139
Category
Article
ISSN
0014-5793

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The time course of the phosphorylation of proteins in the synaptic plasma membrane and the effect of certain cations
✍ Malcolm Weller 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 637 KB

The phosphorylation of proteins in the synaptic plasma membrane is a rather slow reaction taking several minutes to saturate all the phosphate acceptor sites. (The time for half the protein bound phosphate groups to turnover is about 1 min). A divalent cation is needed as a cofactor for the reaction