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The Effect of Different Dosing Schedules of UCN-01 on its Pharmacokinetics and Cardiohaemodynamics in Dogs

✍ Scribed by N. KURATA; S. IMABEPPU; M. NITOH; H. KOBAYASHI; T. KUWABARA; S. KOBAYASHI

Book ID
111768575
Publisher
Pharmaceutical Press
Year
2000
Tongue
English
Weight
138 KB
Volume
52
Category
Article
ISSN
2042-7158

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## Abstract In order to determine the potential pharmacokinetic drug interaction between ranitidine and diltiazem (DTZ), each of ten male beagle dogs, age 2Β·7–4Β·0 years, weight 13–16 kg, received a single oral dose of sustained release DTZ with and without previous multiple oral doses of ranitidine