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The effect of diazepam on indices of 5-HT function in man

✍ Scribed by D.J. Nutt; P.J. Cowen; M. Franklin; P. Murdock; B. Gosden; S. Fraser

Book ID: 113220638
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 406 KB
Volume: 24
Category: Article
ISSN: 0091-3057
DOI: 10.1016/0091-3057(86)90217-0

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## Abstract Administration of l‐tryptophan (TRP), the amino acid precursor of 5‐hydroxytryptamine (5‐HT), to animals increases brain 5‐HT synthesis and in some circumstances, the release of 5‐HT in terminal fields. TRP also appears to increase brain 5‐HT neurotransmission in humans because neuroend