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THE EFFECT OF CYP2D6 GENOTYPES ON DRUG INTERACTIONS OF ARIPIPRAZOLE AND HALOPERIDOL IN PATIENTS WITH SCHIZOPHRENIA

✍ Scribed by Joo-Cheol Shim; Do-Un Jung; Tae-Min Ha

Book ID
119557642
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
75 KB
Volume
102
Category
Article
ISSN
0920-9964

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## Abstract ## Objective Risperidone is converted to 9‐hydroxyrisperidone by CYP2D6. Two parameters were used to examine the influences of CYP2D6 polymorphism and of co‐medication on risperidone metabolism: the risperidone:9‐hydroxyrisperidone concentration ratio (R:9‐OHR ratio) and the sum of the