The effect of compounds depressing mitotic cell division on the respiration of rat liver slices
โ Scribed by A. Kish; A. Epereshi; C. Hadnad; I. Chegedi; L. Nemesh; I. Verep'
- Publisher
- Springer US
- Year
- 1960
- Tongue
- English
- Weight
- 111 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0007-4888
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Some aldehydes, produced during lipid peroxidation of liver lipids, are able to inhibit the respiration of mitochondria and of intact cells both in normal hepatocytes and in Yoshida hepatoma. In mitochondria. the respiratory stimulation produced by addition of ADP and dinitrophenol is decreased more
Tumour cells from a squamous carcinoma (approximately 2.5 X 10(5)) were injected intraportally into a syngeneic strain of rats to produce liver metastases 14 days later. Kupffer cells were stimulated by Corynebacterium parvum (7 mg or 1 mg i.v.) and zymosan (10 mg intraportally). Kupffer cell activi