The effect of composite oral treatment for internal contamination with several radionuclides on 131I thyroid uptake in humans
✍ Scribed by I. Šimonović; B. Kargačin; K. Kostial
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 278 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0260-437X
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✦ Synopsis
The efficiency of a composite oral treatment on 1311 thyroid uptake was investigated in three adult volunteers. The treatment consisted of 10 g of calcium alginate, 3 g ferrihexacyanoferrate(II), 130 mg of potassium iodide and 5 g of Zn-DTPA. This mixture when administered 30 min before 1311 almost completely blocked the 1311 thyroid uptake. This indicates that simultaneous administration of other antidotal agents do not cancel or decrease the effect of potassium iodide on I3'I thyroid uptake. The finding deserves attention since composite oral treatment is the recommended therapy in cases of accidental environmental exposure to several radionuclides.