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The effect of combined CJZ3, a lomerizine derivative, with verapamil on P-glycoprotein efflux function in vitro

โœ Scribed by Bian-Sheng Ji; Yan-Li Ren; Ling He


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
87 KB
Volume
72
Category
Article
ISSN
0272-4391

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In Vitro absorption and secretory quotie
โœ Victoria E. Thiel-Demby; Timothy K. Tippin; Joan E. Humphreys; Cosette J. Serabj ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 92 KB ๐Ÿ‘ 1 views

The absorptive (AQ) and secretory (SQ) quotients have been proposed as a novel experimental approach to quantify the modulation of intestinal absorption and secretion by P-glycoprotein (Pgp). Because these unidirectional assays inherently assess for the impact of Pgp, conclusions as to whether a com