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The effect of collateral flow and myocardial viability on the distribution of technetium-99m sestamibi in a closed-chest model of coronary occlusion and reperfusion

✍ Scribed by Panithaya Chareonthaitawee; Michael K. O’Connor; Raymond J. Gibbons; Erik L. Ritman; Timothy F. Christian


Publisher
Springer
Year
2000
Tongue
English
Weight
207 KB
Volume
27
Category
Article
ISSN
0340-6997

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Technetium-99m hexakis-2-methoxyisobutyl isonitrile (99mTc-MIBI) distribution is flow-dependent, permitting the imaging of coronary perfusion defects. However, the behaviour of this tracer in viable and necrotic tissues within the ischaemic area at risk is still being debated. In a clinically releva