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The effect of chlorpromazine on sentence structure of schizophrenic patients

โœ Scribed by Raymond Levy

Publisher
Springer
Year
1968
Tongue
English
Weight
412 KB
Volume
13
Category
Article
ISSN
0033-3158

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โœฆ Synopsis

The effects of chlorpromazine on the sentence structure of four schizophrenic patients is described.

The measure chosen was the "subordination-index" (S.I.) which is a ratio of the number of subordinate propositions to the total number of propositions in a speech sample and is claimed to be an index of hierarchical dependence in sentences.

The patients were studied; a) before treatment; b) after 48 hours on 50 mg chlorpromazine t.d.s.; c) after symptomatic recovery.

After 48 hours on the drug there was a fall in S.L for "abstract" speech and proverb interpretations but no change in descriptive speech and interviews.

Following recovery the S.I. for "abstract" speech, proverb interpretations and interviews all rose above the pre-treatment level but that for descriptive speech remained unchanged.

The significance of the results is discussed.

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