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The effect of chenodeoxycholic acid on the development of aberrant crypt foci in the rat colon

✍ Scribed by Sutherland, Laurie A.M.; Bird, Ranjana P.

Book ID
120665129
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
655 KB
Volume
76
Category
Article
ISSN
0304-3835

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## Abstract AKR/J mice are resistant to the tumorigenic properties of the colon carcinogen, azoxymethane (AOM). Following AOM exposure, limited numbers of preneoplastic lesions, referred to as aberrant crypt foci (ACF), are formed in the colon, and their progression to tumors rarely occurs. To dete