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The effect of chemotherapy or radiotherapy on thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in cancer of the uterine cervix

โœ Scribed by Kiyoshi Hasegawa; Harumi Okamoto; Kyoko Kawamura; Rina Kato; Yoichi Kobayashi; Takao Sekiya; Yasuhiro Udagawa


Book ID
119234258
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
181 KB
Volume
163
Category
Article
ISSN
0301-2115

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## Abstract ## Objectives: To evaluate whether two molecular biomarkers, thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD), could be clinically useful in predicting and improving the chemotherapeutic outcome of the oral fluoropyrimidine capecitabine (5โ€ฒโ€DFUR or Xelodaยฎ), in th