𝔖 Bobbio Scriptorium
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The effect of carboxylesterase inhibition on interspecies differences in soman toxicity

✍ Scribed by Maxwell, Donald M.; Brecht, Karen M.; O'Neill, Barbara L.


Book ID
121360846
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
494 KB
Volume
39
Category
Article
ISSN
0378-4274

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Iso-OMPA-induced potentiation of soman t
✍ Zoran Grubič; DuΕ‘an Sket; Miro Brzin πŸ“‚ Article πŸ“… 1988 πŸ› Springer-Verlag 🌐 English βš– 158 KB

Recently, the question was raised as to why iso-OMPA, generally known as a selective irreversible inhibitor of butyrylcholinesterase (BuChE), potentiates soman toxicity in rats but not in mice. Mice are known to have higher carboxylesterase (CarbE) and lower BuChE activity in plasma than rat. It cou