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The effect of calcium and magnesium ions on urinary urokinase and sialidase activity

✍ Scribed by van Aswegen, C. H. ;Dirksen van Sckalckwyk, J. C. ;du Toit, P. J. ;Verster, L. ;Franz, R. C. ;du Plessis, D. J.

Publisher
Springer
Year
1992
Tongue
English
Weight
361 KB
Volume
20
Category
Article
ISSN
0300-5623

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✦ Synopsis

The effect of a promoter (calcium) and an inhibitor (magnesium) of urolithiasis was spectrophotometrically studied on urokinase (0.45 IU) and sialidase (5 mM). Although these mineral did not affect the sialidase activity, total inhibition of urokinase activity was observed with either 0.05 M calcium chloride or 0.1 M magnesium chloride. This observation might explain why calcium and magnesium respectively function as a promoter and an inhibitor of stone formation.

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