Casodex' (bicalutamide) is an orally active, non-steroidal, pure antiandrogen; it is a racemate with antiandrogenic activity residing predominantly in the (R)-enantiomer. Healthy male volunteers (n=15) were administered single oral doses of bicalutamide (50 mg) after food and after fasting as part o
The effect of bicalutamide on prostate histology
โ Scribed by Lars Magne Eri; Aud Svindland; Kjell J. Tveter
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 275 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0270-4137
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๐ SIMILAR VOLUMES
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## Background: Although essential, androgens alone are not sufficient to induce normal growth and functionality of the prostate. nonandrogenic hormones must also be involved in the proliferation of the prostate cancer cells which do not respond to antiandrogenic therapy and which thus become androg
BACKGROUND. Bicalutamide (Casodex) is a new nonsteroidal antiandrogen developed for use in patients with prostate cancer. The efficacy and tolerability of bicalutamide as monotherapy and as combination therapy for patients with advanced prostate cancer have been evaluated in randomized clinical tria
We collected data on the histologic grade, stage, and age at diagnosis of 4,114 cases of prostate cancer (1,380 blacks, and 2,734 whites) in the Chicago area. The relationship between histologic grade (high = poorly or undifferentiated vs. low = well or moderatly differentiated) and race (black vs.