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The effect of beta-adrenoceptor antagonists on the pharmacokinetics and pharmacodynamics of warfarin.

✍ Scribed by ND Bax; MS Lennard; GT Tucker; HF Woods; NR Porter; RG Malia; FE Preston

Book ID
117943488
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
123 KB
Volume
17
Category
Article
ISSN
0306-5251

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## Abstract The effect of hydralazine on the pharmacokinetics of metoprolol, nadolol, and acebutolol has been studied by measuring drug concentrations in plasma, serum, and urine. Metoprolol is affected by hydralazine, the AUC and __C__~max~ being significantly increased. The kinetics of acebutolol