## Retinoids -Peritoneal exsudate cells Retinoids are naturally occurring and synthetic analogues of vitamin A and possess antineoplastic activities in vivo together with therapeutic efficacy in a number of dermatologic diseases [6]. Furthermore, they are involved in the maintenance and differenti
The effect of aromatic retinoid RO 10-9359 (etretinate) on fingernail growth
β Scribed by A. Galosi; G. Plewig; O. Braun-Falco
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 377 KB
- Volume
- 277
- Category
- Article
- ISSN
- 0340-3696
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β¦ Synopsis
Fingernail growth was studied in 28 patients who were receiving systemic treatment with the aromatic retinoid, Ro 10-9359 known as Tigason (etretinate; AR). A group of 15 patients with psoriasis was compared with a group of 13 patients with other dermatoses which are known to have a good response to AR therapy. In the second group, oral therapy with AR appeared to have no effect on the daily growth rate of fingernails (99 +_ 4 gm). With AR treatment, the nail-plate growth rate in the psoriatics increased to 132 + 5 gm.
π SIMILAR VOLUMES
The therapeutic effect of an aromatic retinoic acid analogue (Ro 10-9359) and mitomycin C (MMC) on rats with bladder tumours induced by N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) was examined. Eight-week-old female Wistar rats were given 0.05% BBN in drinking water for 8 weeks. Therapy was started