The specificity of antibodies offers unique opportunities to target tumors with radionuclides. However, due to the slow clearance of radiolabeled antibody, relatively high background is observed in non-target organs. Pre-targeting protocols using bispecific monoclonal antibodies (bsMAbs) and radiola
The effect of antibody protein dose of anti-renal cell carcinoma monoclonal antibodies in nude mice with renal cell carcinoma xenografts
✍ Scribed by Marion H. G. C. Kranenborg; Otto C. Boerman; Mirjam C. A. de Weijert; Jeannette C. Oosterwijk-Wakka; Frans H. M. Corstens; Egbert Oosterwijk
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 164 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
RESULTS.
The relative uptake of G250 in NU-12 tumors was very high at low protein doses (125% injected dose/g [%ID/g]), but decreased at higher doses, suggesting
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