The effect of amino acid depletion or supplementation and the effect of glucagon and insulin on the amino acid transport mediated by s stem A were acid (AIB) or N-methyl 2-amino [l-'4C]isobutyric acid (MeAIB) in rat hepatocytes, freshly isolated at different stages of pre-and postnatal development.
The effect of amiloride on hormonal regulation of amino acid transport in isolated and cultured adult rat hepatocytes
β Scribed by Max Fehlmann; Michael Samson; Katherine S. Koch; Hyam L. Leffert; Pierre Freychet
- Book ID
- 115725021
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 518 KB
- Volume
- 642
- Category
- Article
- ISSN
- 0005-2736
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The present report shows that System A-mediated 2-aminoisobutyric acid (AIB) uptake is elevated in hepatocytes isolated from adrenalectomized rats when they are compared to control cells. Although System ASC activity also shows this perturbation, Systems N, p, L1, and L2 are unaffected. Transport of
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