The effect of adaptation to mice on the antigenicity of influenza virus
β Scribed by Isaacs, A. ;de C. Sampaio, A. A.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1953
- Tongue
- English
- Weight
- 178 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0368-3494
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Earlier we reported that both actively replicating (A2 and B) and live but nonreplicating (C) strains of influenza virus induced significant percentages of chromosome aberrations in the spermatogonia of the infected mice, suggesting that virus replication was not essential for the induction of chrom
Swiss albino male mice were administered two doses (1 and 2 HA units) of influenza A2 Hong Kong/68 virus IP. The incidence of chromosomal anomalies in spermatocytes was analysed at various times post infection and was found to be significantly higher than in controls, indicating that the influenza v