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The effect of acrylonitrile on gap junctional intercellular communication in rat astrocytes

โœ Scribed by L.M. Kamendulis; J. Jiang; H. Zhang; H. deFeijter-Rupp; J.E. Trosko; J.E. Klaunig

Book ID
110253221
Publisher
Springer
Year
1999
Tongue
English
Weight
119 KB
Volume
15
Category
Article
ISSN
0742-2091

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Many nongenotoxic hepatocarcinogens can induce cell proliferation, and inhibit apoptosis and gap-junctional-intercellular communication (GJIC). GJIC, the movement of small molecules (less than 1.2 kD) through membrane channels, is important in regulating cellular homeostasis and differentiation. The