The effect of a single sub-acute x-ray exposure to the fetus on skeletal growth; a quantitative study
✍ Scribed by Barnet M. Levy; Roberts Rugh; Lois Lunin; Neal Chilton; Melvin Moss
- Publisher
- John Wiley and Sons
- Year
- 1953
- Tongue
- English
- Weight
- 547 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0362-2525
No coin nor oath required. For personal study only.
✦ Synopsis
With the increasing use of ionizing radiations in diagnosis and therapy, one may predict that more and more human embryos and fetuses will be exposed to x-radiation. It is important, therefore, that data be accumulated relative to the radiosensitivities of specific organ primordia. It is apparent that the developmental stage at which x-irradiation is applied is more important than the intensity of the x-irradiation (Russell, '50 ; Wilson, '51 ; Hicks, ' 5 3 ) .
'This project was initiated to determine the effect on skeletal development of a single x-ray exposure at the high but subacute level of 300 r to the mouse fetus at 154 days of gestation.
At this stage of development the primary centers of ossification of the bones of the mouse fetus are evident. Any radiation effects would therefore be on the process of growth rather than on initial differentiation.
There are many papers dealing with the effects of x-irradiation of the embryo (Russell, '50; Wilson, '51; Wilson et al., '53). Recently, Hicks ( '53) described the effects of x-irradia-* Department of Dentistry.