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The effect of 4-amino-5-imidazolecarboxamide on the synergistic antineoplastic activity of 6-chloropurine and azaserine

✍ Scribed by A. C. Sartorelli; Barbara A. Booth

Book ID
112701959
Publisher
Springer
Year
1965
Tongue
English
Weight
290 KB
Volume
21
Category
Article
ISSN
1420-682X

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Studies on the reversal of the selective
Studies on the reversal of the selective antitumour effect of the aziridinyl derivative cb 1954 by 4-amino-5-imidazolecarboxamide
✍ T. A. Connors; H. G. Mandel; D. H. Melzack πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 French βš– 435 KB

## Abstract The selective toxicity of CB 1954 (5‐aziridinyl‐2,4‐dinitrobenzamide) for Walker tumour cells, previously shown in the whole animal and in an in vitro/in vivo system, has been confirmed in an in vitro system In each case its actions on the Walker tumour were reversed by 4‐amino‐5‐imidaz