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The EF-hand calcium-binding protein calmyrin inhibits the transcriptional and DNA-binding activity of Pax3

✍ Scribed by Andrew D. Hollenbach; Craig J. McPherson; Irina Lagutina; Gerard Grosveld


Book ID
114147494
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
381 KB
Volume
1574
Category
Article
ISSN
0167-4781

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## Abstract Positive cooperativity, defined as an enhancement of the ligand affinity at one site as a consequence of binding the same type of ligand at another site, is a free energy coupling between binding sites. It can be present both in systems with sites having identical ligand affinities and